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1.

The microbiota coordinates diurnal rhythms in innate immunity with the circadian clock.

Brooks, John F; Behrendt, Cassie L; Ruhn, Kelly A; Lee, Syann; Raj, Prithvi; Takahashi, Joseph S; Hooper, Lora V.

Cell; 184(16): 4154-4167.e12, 2021 08 05.

Artículo en Inglés | MEDLINE | ID: mdl-34324837

2.

Molecular basis for retinol binding by serum amyloid A during infection.

Hu, Zehan; Bang, Ye-Ji; Ruhn, Kelly A; Hooper, Lora V.

Proc Natl Acad Sci U S A; 116(38): 19077-19082, 2019 09 17.

Artículo en Inglés | MEDLINE | ID: mdl-31484771

3.

Epithelial retinoic acid receptor ß regulates serum amyloid A expression and vitamin A-dependent intestinal immunity.

Gattu, Sureka; Bang, Ye-Ji; Pendse, Mihir; Dende, Chaitanya; Chara, Andrew L; Harris, Tamia A; Wang, Yuhao; Ruhn, Kelly A; Kuang, Zheng; Sockanathan, Shanthini; Hooper, Lora V.

Proc Natl Acad Sci U S A; 116(22): 10911-10916, 2019 05 28.

Artículo en Inglés | MEDLINE | ID: mdl-31097581

4.

Resistin-like molecule ß is a bactericidal protein that promotes spatial segregation of the microbiota and the colonic epithelium.

Propheter, Daniel C; Chara, Andrew L; Harris, Tamia A; Ruhn, Kelly A; Hooper, Lora V.

Proc Natl Acad Sci U S A; 114(42): 11027-11033, 2017 10 17.

Artículo en Inglés | MEDLINE | ID: mdl-28973871

5.

Gammadelta intraepithelial lymphocytes are essential mediators of host-microbial homeostasis at the intestinal mucosal surface.

Ismail, Anisa S; Severson, Kari M; Vaishnava, Shipra; Behrendt, Cassie L; Yu, Xiaofei; Benjamin, Jamaal L; Ruhn, Kelly A; Hou, Baidong; DeFranco, Anthony L; Yarovinsky, Felix; Hooper, Lora V.

Proc Natl Acad Sci U S A; 108(21): 8743-8, 2011 May 24.

Artículo en Inglés | MEDLINE | ID: mdl-21555560

6.

Analysis of inflammation-related nigral degeneration and locomotor function in DJ-1(-/-) mice.

Nguyen, Thi A; Frank-Cannon, Tamy; Martinez, Terina N; Ruhn, Kelly A; Marvin, Marian; Casey, Bradford; Treviño, Isaac; Hong, John J; Goldberg, Matthew S; Tansey, Malú G.

J Neuroinflammation; 10: 50, 2013 Apr 28.

Artículo en Inglés | MEDLINE | ID: mdl-23622116

7.

The gut microbiota reprograms intestinal lipid metabolism through long noncoding RNA Snhg9.

Wang, Yuhao; Wang, Meng; Chen, Jiaxin; Li, Yun; Kuang, Zheng; Dende, Chaitanya; Raj, Prithvi; Quinn, Gabriella; Hu, Zehan; Srinivasan, Tarun; Hassell, Brian; Ruhn, Kelly A; Behrendt, Cassie L; Liang, Tingbo; Dou, Xiaobing; Song, Zhangfa; Hooper, Lora V.

Science; 381(6660): 851-857, 2023 08 25.

Artículo en Inglés | MEDLINE | ID: mdl-37616368

8.

Macrophages regulate gastrointestinal motility through complement component 1q.

Pendse, Mihir; De Selle, Haley; Vo, Nguyen; Quinn, Gabriella; Dende, Chaitanya; Li, Yun; Salinas, Cristine N; Srinivasan, Tarun; Propheter, Daniel C; Crofts, Alexander A; Koo, Eugene; Hassell, Brian; Ruhn, Kelly A; Raj, Prithvi; Obata, Yuuki; Hooper, Lora V.

Elife; 122023 04 26.

Artículo en Inglés | MEDLINE | ID: mdl-37159507

9.

Delayed dominant-negative TNF gene therapy halts progressive loss of nigral dopaminergic neurons in a rat model of Parkinson's disease.

Harms, Ashley S; Barnum, Christopher J; Ruhn, Kelly A; Varghese, Steve; Treviño, Isaac; Blesch, Armin; Tansey, Malú G.

Mol Ther; 19(1): 46-52, 2011 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-20959812

10.

Serum amyloid A delivers retinol to intestinal myeloid cells to promote adaptive immunity.

Bang, Ye-Ji; Hu, Zehan; Li, Yun; Gattu, Sureka; Ruhn, Kelly A; Raj, Prithvi; Herz, Joachim; Hooper, Lora V.

Science; 373(6561): eabf9232, 2021 Sep 17.

Artículo en Inglés | MEDLINE | ID: mdl-34529485

11.

Small proline-rich protein 2A is a gut bactericidal protein deployed during helminth infection.

Hu, Zehan; Zhang, Chenlu; Sifuentes-Dominguez, Luis; Zarek, Christina M; Propheter, Daniel C; Kuang, Zheng; Wang, Yuhao; Pendse, Mihir; Ruhn, Kelly A; Hassell, Brian; Behrendt, Cassie L; Zhang, Bo; Raj, Prithvi; Harris-Tryon, Tamia A; Reese, Tiffany A; Hooper, Lora V.

Science; 374(6568): eabe6723, 2021 Nov 05.

Artículo en Inglés | MEDLINE | ID: mdl-34735226

12.

Regulator of G-protein signaling 10 promotes dopaminergic neuron survival via regulation of the microglial inflammatory response.

Lee, Jae-Kyung; McCoy, Melissa K; Harms, Ashley S; Ruhn, Kelly A; Gold, Stephen J; Tansey, Malú G.

J Neurosci; 28(34): 8517-28, 2008 Aug 20.

Artículo en Inglés | MEDLINE | ID: mdl-18716210

13.

Parkin deficiency increases vulnerability to inflammation-related nigral degeneration.

Frank-Cannon, Tamy C; Tran, Thi; Ruhn, Kelly A; Martinez, Terina N; Hong, John; Marvin, Marian; Hartley, Meagan; Treviño, Isaac; O'Brien, Daniel E; Casey, Bradford; Goldberg, Matthew S; Tansey, Malú G.

J Neurosci; 28(43): 10825-34, 2008 Oct 22.

Artículo en Inglés | MEDLINE | ID: mdl-18945890

14.

Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology.

McAlpine, Fiona E; Lee, Jae-Kyung; Harms, Ashley S; Ruhn, Kelly A; Blurton-Jones, Mathew; Hong, John; Das, Pritam; Golde, Todd E; LaFerla, Frank M; Oddo, Salvatore; Blesch, Armin; Tansey, Malú G.

Neurobiol Dis; 34(1): 163-77, 2009 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-19320056

15.

Intranigral lentiviral delivery of dominant-negative TNF attenuates neurodegeneration and behavioral deficits in hemiparkinsonian rats.

McCoy, Melissa K; Ruhn, Kelly A; Martinez, Terina N; McAlpine, Fiona E; Blesch, Armin; Tansey, Malú G.

Mol Ther; 16(9): 1572-9, 2008 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-18628756

16.

The intestinal microbiota programs diurnal rhythms in host metabolism through histone deacetylase 3.

Kuang, Zheng; Wang, Yuhao; Li, Yun; Ye, Cunqi; Ruhn, Kelly A; Behrendt, Cassie L; Olson, Eric N; Hooper, Lora V.

Science; 365(6460): 1428-1434, 2019 09 27.

Artículo en Inglés | MEDLINE | ID: mdl-31604271

17.

Resistin-like Molecule α Provides Vitamin-A-Dependent Antimicrobial Protection in the Skin.

Harris, Tamia A; Gattu, Sureka; Propheter, Daniel C; Kuang, Zheng; Bel, Shai; Ruhn, Kelly A; Chara, Andrew L; Edwards, Marshall; Zhang, Chenlu; Jo, Jay-Hyun; Raj, Prithvi; Zouboulis, Christos C; Kong, Heidi H; Segre, Julia A; Hooper, Lora V.

Cell Host Microbe; 25(6): 777-788.e8, 2019 Jun 12.

Artículo en Inglés | MEDLINE | ID: mdl-31101494

18.

Neuroinflammation in Parkinson's disease: is there sufficient evidence for mechanism-based interventional therapy?

Tansey, Malú G; Frank-Cannon, Tamy C; McCoy, Melissa K; Lee, Jae Kyung; Martinez, Terina N; McAlpine, Fiona E; Ruhn, Kelly A; Tran, Thi A.

Front Biosci; 13: 709-17, 2008 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-17981581

19.

Blocking soluble tumor necrosis factor signaling with dominant-negative tumor necrosis factor inhibitor attenuates loss of dopaminergic neurons in models of Parkinson's disease.

McCoy, Melissa K; Martinez, Terina N; Ruhn, Kelly A; Szymkowski, David E; Smith, Christine G; Botterman, Barry R; Tansey, Keith E; Tansey, Malú G.

J Neurosci; 26(37): 9365-75, 2006 Sep 13.

Artículo en Inglés | MEDLINE | ID: mdl-16971520

20.

The intestinal microbiota regulates body composition through NFIL3 and the circadian clock.

Wang, Yuhao; Kuang, Zheng; Yu, Xiaofei; Ruhn, Kelly A; Kubo, Masato; Hooper, Lora V.

Science; 357(6354): 912-916, 2017 09 01.

Artículo en Inglés | MEDLINE | ID: mdl-28860383

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